The final report of the Outcome-Focused Learning Review for the Green Resilient Agriculture Productive Ecosystems (GRAPE-FA2) project presents a comprehensive framework, detailing the project’s context, methodology, and a thorough review of project documents. It also incorporates finding and discussions derived from both the review process and field data collection from the project areas. Led by ICIMOD in collaboration with Local Initiatives for Biodiversity Research and Development (Li-BIRD), Center for Environmental and Agricultural Policy Research, Extension, and Development (CEAPRED), Agriculture and Forest University (AFU), Mid- West University, and Far-Western University (FWU), the GRAPE-FA2 project aims to enhance the sustainability and resilience of agro-ecosystems in Sudurpaschim and Karnali Provinces. The project focuses on innovation and capacity building, which includes testing and promoting climate-resilient farming practices, generating evidence-based knowledge, and scaling effective solutions in these regions.